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  DOLO-650
 Manufacturer Micro Labs Ltd.
 Generic Paracetamol
 Package/s Tablet 650 mg, (Rs. 16.00)
 About Paracetamol Acetanilide derivative, Non narcotic Analgesic,Antipyretic. More details.....
 Dosage Adult: 500 - 1000 mg in 3 times daily Maximum dose: 4 g / day For migraine: 500 mg to be taken at the first sign of migraine attack and repeated 4....More details.....
 Pregnancy Use with caution
 Breast Feeding Use with caution
 Old Age Use with caution
 Children Use with caution NEONATES : Contraindicated
 Mechanism Of Action Paracetamol has analgesic and antipyretic action. It is more active on cyclo-oxygenase enzyme in brain. Peripherally it is a poor inhibitor of prost....More details.....
 PharmacoKinetics Absorption: Paracetamol is rapidly and completely absorbed after oral administration. Distribution: It is distributed mostly in the body in unbound ....More details.....
 OnsetOfAction 30 - 60 minutes....More details.....
 DurationOfAction 6 hours....More details.....
 AdverseEffect 1. Nausea 2. Abdominal distress 3. Allergic reactions 4. Rash ....More details.....
 SpecialPrecautions 1. Hepatic impairment 2. Renal impairment 3. Hypertension ....More details.....
 Indications 1. To relieve pain and fever 2. Acute gout 3. Migraine ....More details.....
 Interactions Cholestyramine: Reduces absorption of paracetamol. Charcoal: Activated, administered immediately reduces absorption of paracetamol. Domperidone and ....More details.....
 Storage Store at 15-30 degree C in a tightly closed container. Protect from heat and moisture. Keep out of the reach of children.....More details.....
 MissedDosage Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.....More details.....
 Overdose Give supportive measures and symptomatic treatment. Drug can be removed from the body by gastric lavage or by inducing emesis. Absorption of the drug can be reduced by administration of activated charcoal. N-acetylcysteine is the specific antidote for Paracetamol poisoning. Dose: 150 mg /kg body weight as IV infusion over 15 minutes followed by same dose over 20 hours. Maintenance dose: 75 mg / kg orally every 4 - 6 hours for 2 - 3 days. Haemodialysis can be done in emergency conditions. ....More details.....
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