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| ONDEM MD 4 | ||||||||||||||||||||
| Manufacturer | Alkem Laboratries Ltd. | |||||||||||||||||||
| Generic | Ondansetron | |||||||||||||||||||
| Package/s | Tablet 4 mg, (Rs. 52.00) | |||||||||||||||||||
| About Ondansetron | Selective serotonin 5-HT3 receptor antagonist, Imidazole derivative, Antiemetic. More details..... | |||||||||||||||||||
| Dosage | Adult: Oral : Nausea and vomiting associated with cytotoxic chemotherapy or radiotherapy:8 mg should be given 1 - 2 hour before chemotherapy or rad....More details..... | |||||||||||||||||||
| Pregnancy | Contraindicated | |||||||||||||||||||
| Breast Feeding | Use with caution | |||||||||||||||||||
| Old Age | May be used | |||||||||||||||||||
| Children | Use with caution Below 6 months : Contraindicated | |||||||||||||||||||
| Mechanism Of Action | Ondansetron is a selective 5HT3 receptor antagonist. 5HT3 receptors are present in vagal nerve terminals and chemoreceptor trigger zone of area postre....More details..... | |||||||||||||||||||
| PharmacoKinetics | Absorption: Ondansetron is well absorbed after oral administration and the bioavailability is 50 - 60 %. Distribution: It is distributed in protein ....More details..... | |||||||||||||||||||
| OnsetOfAction | With in 30 minutes....More details..... | |||||||||||||||||||
| DurationOfAction | 8 - 10 hours....More details..... | |||||||||||||||||||
| AdverseEffect | 1. Headache 2. Dizziness 3. Constipation 4. Musculoskeletal pain 5. Chills 6. Allergic reactions 7. Agitation 8. Chest pain 9. Malaise 10. Ur....More details..... | |||||||||||||||||||
| SpecialPrecautions | 1. Hepatic impairment 2. Intestinal obstruction ....More details..... | |||||||||||||||||||
| Indications | 1. Nausea and vomiting associated with cytotoxic chemotherapy or radiotherapy. 2. Post operative nausea and vomiting ....More details..... | |||||||||||||||||||
| Interactions | Inducers of hepatic cytochrome P450 drug metabolising enzymes: May change the clearance and hence the half-life of ondansetron, but on the basis of av....More details..... | |||||||||||||||||||
| Storage | Store at room temperature. Protect from heat and light. Keep out of the reach of children.....More details..... | |||||||||||||||||||
| MissedDosage | If you missed a dose and do not feel nauseated then skip the missed dose and go back regular schedule. If you missed a dose and feel nauseated then take the missed dose as soon as possible. ....More details..... | |||||||||||||||||||
| Overdose | Give supportive measures and symptomatic treatment.....More details..... | |||||||||||||||||||
| Substitute Brand's of ONDEM MD 4 | ||||||||||||||||||||
| Price comparison, Drug alerts (Pregnanacy, Breast Feeding, Old Age) and More details..... | ||||||||||||||||||||
| Prices are subject to change | ||||||||||||||||||||
| Disclaimer | ||||||||||||||||||||
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