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| EMDOPA | ||||||||||||||||||||
| Manufacturer | Indian Drugs & Pharmaceuticals Ltd. (IDPL) | |||||||||||||||||||
| Generic | Methyldopa | |||||||||||||||||||
| Package/s | Tablet 250 mg, (Rs. 32.84) | |||||||||||||||||||
| About Methyldopa | Centrally acting Alpha-2 agonist ,a phenylalanine derivative, Antihypertensive (pregnancy-induced hypertension). More details..... | |||||||||||||||||||
| Dosage | Adults: 250mg to 500mg orally 12hourly or 6hourly or 250mg to 500mg I.V. four times daily Children: 10mg/kg/day orally 12hourly or 6hourly or 20 t....More details..... | |||||||||||||||||||
| Pregnancy | May be used. | |||||||||||||||||||
| Breast Feeding | May be used. | |||||||||||||||||||
| Old Age | Use with caution. | |||||||||||||||||||
| Children | Use with caution | |||||||||||||||||||
| Mechanism Of Action | Methyl dopa gets metabolized in the adrenergic neurons to alpha methyl nor adrenaline which acts centrally by stimulating alpha 2 adrenergic receptors....More details..... | |||||||||||||||||||
| PharmacoKinetics | Absorption: About half of the drug administered is absorbed orally, Distribution: Widely distributed, Metabolism: Extensively metabolized in liver & ....More details..... | |||||||||||||||||||
| OnsetOfAction | 4 to 6 hours....More details..... | |||||||||||||||||||
| DurationOfAction | 1 to 3 days....More details..... | |||||||||||||||||||
| AdverseEffect | 1.Sedation 2.Mental depression 3.Dryness of mouth, eyes & nose 4.Cognitive impairment 5.Impotence 6.Dizziness 7.Insomnia 8.Constipation 9.Elec....More details..... | |||||||||||||||||||
| SpecialPrecautions | 1.Renal impairment 2.Hepatic impairment 3.Haemolytic anaemia 4.Some individuals may show +ve direct coomb`s test 5.Parkinsonism 6.Asses blood cou....More details..... | |||||||||||||||||||
| Indications | 1.Hypertension....More details..... | |||||||||||||||||||
| Interactions | Haloperidol: Adverse mental symptoms and high incidence of sedation. Levodopa: Effects of levodopa potentiated. Corticosteroids & Carbenoxolone: An....More details..... | |||||||||||||||||||
| Storage | Store at room temperature in a well closed container. Protect from heat and light. Keep out of the reach of children.....More details..... | |||||||||||||||||||
| MissedDosage | Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose....More details..... | |||||||||||||||||||
| Overdose | Treatment is supportive and symptomatic. After 4hours of drug use empty the stomach by induced emesis & gastric lavage. Administer activated charcoal. Perform haemodialysis if required.....More details..... | |||||||||||||||||||
| Substitute Brand's of EMDOPA | ||||||||||||||||||||
| Price comparison, Drug alerts (Pregnanacy, Breast Feeding, Old Age) and More details..... | ||||||||||||||||||||
| Prices are subject to change | ||||||||||||||||||||
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