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  ISOPTIN RETARD
 Manufacturer Abbott Laboratories (India) Pvt. Ltd.
 Generic Verapamil
 Package/s Tablet 240 mg, (Rs. .00)
 About Verapamil Calcium channel blocker, phenylalkylamine derivative, Class IV Antiarrhythmic, antihypertensive. More details.....
 Dosage Oral: 120 to 320mg/day in 3 to 4 divided doses. Maximum dose: 480mg/day I.V.: Starts with 5mg. Repeat the therapy with same dose after 5 to 10minute....More details.....
 Pregnancy Use with caution
 Breast Feeding Contraindicated
 Old Age Use with caution
 Children Use with caution
 Mechanism Of Action Verapamil is a phenylalkylamine; Ca channel blocker. It exerts it`s antianginal, antihypertensive, antiarrythmic actions through blocking the influx o....More details.....
 PharmacoKinetics Absorption: Well absorbed orally, bioavailability is reduced due to first pass metabolism. Distribution: Widely distributed in a protein bound form.....More details.....
 OnsetOfAction I.V.:2 to 3 minutes Oral: Half an hour ....More details.....
 DurationOfAction 8 to 12 hours....More details.....
 AdverseEffect 1. Bradycardia 2. Worsens heart failure 3. Transient asystole 4. Constipation 5. Hypotension 6. Palpitation 7. Flushing 8. Nausea 9. Edema 1....More details.....
 SpecialPrecautions 1. Bradycardia 2. Hypotension 3. Hypertrophic cardiomyopathy 4. Conduction disturbance 5. Impaired left ventricular function 6. Congestive heart ....More details.....
 Indications 1. Paroxysmal supraventricular tachycardia 2. Atrial fibrillation 3. Atrial flutter 4. Angina 5. Hypertension 6. Hypertrophic cardiomyopathy 7. ....More details.....
 Interactions Histamine H2 antagonists: May enhance bioavailability. B-Blockers: Though advantageous in some, concomitant use results in increased adverse effects ....More details.....
 Storage Store in a cool dry place below 25 degree C. Protects from light.....More details.....
 MissedDosage Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.....More details.....
 Overdose Treatment is supportive and symptomatic. Remove drug from the stomach by gastric lavage. Reduce absorption by administering activated charcoal Monitor &support cardiac and respiratory functions. Measure the BP. Give cardiovascular support by elevating the limbs and maintaining fluid balance. Administer vasopressers like nor epinephrine if required to treat hypotension. Treat Bradycardia with atropine. Administer isoproterenol with caution if required. Treat heart block with cardiac pacing. Treat cardiac failure with ionotropic agents such as isoproterenol, dopamine, dobutamine etc and diuretics.....More details.....
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