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  NITROCONTIN
 Manufacturer Modi-Mundi Pharma Limited
 Generic Glyceryl Trinitrate
 Package/s Tablet Controlled Release 2.6 mg, (Rs. 90.25)
  Tablet Controlled Release 6.4 mg, (Rs. 118.00)
 About Glyceryl Trinitrate A vasodilator, Antianginal,in CHF. More details.....
 Dosage Tablets: 0.5mg at every 3 minutes until therapeutic effect is obtained. I.V.: 5mcg/minute as infusion. Increase with increments of same dose Sustain....More details.....
 Pregnancy Use with caution
 Breast Feeding Use with caution
 Old Age Use with caution
 Children Contraindicated
 Mechanism Of Action It is a direct smooth muscle relaxant, which have a prominent action vascular smooth muscles preferentially veins than arteries. It is enzymatically d....More details.....
 PharmacoKinetics Absorption: Well absorbed orally, But bioavailability is reduced due to first pass metabolism. Distribution: Widely distributed in the body. Metab....More details.....
 OnsetOfAction Sub lingual: 1 to 3 minutes I.V.: 1 to 2 minutes Topical: 30 to 60 minutes Sustained release: 20 to 45 minutes ....More details.....
 DurationOfAction Sub lingual: 30 to 60 minutes I.V.: 3 to 5 minutes Topical: 2 to 12hours Sustained release: 3to 8hours ....More details.....
 AdverseEffect 1. Headache 2. Weakness 3. Dizziness 4. Methaemoglobinaemia 5. Flushing 6. Palpitation 7. Orthostatic hypotension 8. Sweating 9. Sub lingual b....More details.....
 SpecialPrecautions 1. Gradually withdraw the drug with caution, start therapy with lower doses 2. Hypotension 3. Blood volume depletion 4. Cardio vascular diseases 5....More details.....
 Indications 1. Angina pectoris 2. Unstable angina 3. Heart failure 4. Myocardial infarction 5. Hypertension ....More details.....
 Interactions Alcohol: Severe hypotension and cardiovascular collapse. Aspirin: Increase serum concentrations of nitrates and their actions. Antihypertensives, TC....More details.....
 Storage Store in a well closed container at a temperature below 25 degree C. Protects from light....More details.....
 MissedDosage Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.....More details.....
 Overdose Treatment is supportive and symptomatic. Remove drug from the body by gastric lavage and administer activated charcoal to reduce absorption. Monitor blood gas measurements and methemoglobin levels. Supportive measures include respiratory support and oxygen administration. Recumbent positioning and passive movements of the extremities aid venous return. Maintain adequate body temperature and administer I.V. fluids. Administer adrenergic agonist like phenylephrine if required. For Methaemoglobinaemia; methylene blue may be given.....More details.....
Substitute Brand's of NITROCONTIN
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