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  PACITANE
 Manufacturer Wyeth Lederle Limited
 Generic Trihexyphenidyl
 Package/s Tablet 2 mg, (Rs. 13.78)
 About Trihexyphenidyl Anticholinergic(antimuscarinic), Anti-Parkinson`s Agent ,synthetic antispasmodic. More details.....
 Dosage Adult: Idiopathic Parkinsonism: initial dose: 1mg / day gradually increase the dose every 3 - 5 days up to 10 - 15 mg /day in 3 - 4 divided doses. ....More details.....
 Pregnancy Contraindicated
 Breast Feeding Use with caution
 Old Age Use with caution
 Children Contraindicated NEONATES : Contraindicated
 Mechanism Of Action Trihexyphenidyl is a synthetic Atropine substitute. It produces antiparkinsonian action by blocking the central cholinergic receptors. It inhibits cer....More details.....
 PharmacoKinetics Absorption: It is rapidly absorbed after oral administration. Distribution: It crosses the blood brain barrier. Excretion: It is excreted in urine....More details.....
 OnsetOfAction 1 hour....More details.....
 DurationOfAction 6 - 12 hours....More details.....
 AdverseEffect 1. Dry mouth 2. Nausea 3. Vomiting 4. Constipation 5. Abdominal cramps 6. Dizziness 7. Headache 8. Nervousness 9. Drowsiness 10. Blurred visi....More details.....
 SpecialPrecautions 1. Renal impairment 2. Hepatic impairment 3. Cardiac impairment 4. Gastrointestinal obstructive disease 5. Genitourinary obstructive disease 6. ....More details.....
 Indications 1. Parkinsonism (idiopathic and drug induced Parkinsonism)....More details.....
 Interactions Amantadine: Increased incidence of anticholinergic side effects which disappear on reducing the dose of trihexiphenidyl. Digoxin: Serum levels of dig....More details.....
 Storage Store at 15 - 30 degree C....More details.....
 MissedDosage Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.....More details.....
 Overdose Give supportive measures and symptomatic treatment. Drug can be removed from the body by gastric lavage or inducing emesis. Absorption of the drug can be reduced by administration of activated charcoal. Control excitement with Diazepam (IV). Physostigmine is given to counteract the antimuscarinic effect of Trihexyphenidyl. ....More details.....
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